Anno III
Novembre dicembre 2003
n. 11-12

Pag. 8 di 16

  • ESTERO
         
      The Life Goals Program

     
    A Psychosocial Intervention to Promote Treatment Adherence
                                     
    in a Community Mental Health Clinic

By: Martha Sajatovic MD and Mark Bauer MD

Case Western Reserve University Department of Psychiatry is located in Cleveland, Ohio.  Additional information regarding research studies and Departmental activities is available on the internet at www.cwru.edu/med/psychiatry

The Life Goals Program is structured group psychotherapy for individuals with manic-depressive (bipolar disorder) developed by Dr. Mark Bauer MD and Linda McBride MSN.  Dr. Bauer is currently on the full-time faculty of the Department of Psychiatry and Human Behaviour of Brown University, and on staff in the Mental Health and Behavioural Sciences Services of the Department of Veterans Affairs Medical Center Providence, Rhode Island, U.S. A.  Linda McBride is a Clinical Nurse Specialist in the Mental Health and Behavioural Sciences Service of the Providence Rhode Island Department of Veterans Affairs Medical Center.  The Life Goals Program was developed to assist individuals with bipolar disorder to participate more effectively in the management of their own illness.  Additionally, the Life Goals Program is designed to improve the social and work-related problems that often develop for individuals with bipolar illness.
The Life Goals Program is available in book form, and has recently been released in a second edition (Bauer MS, McBride L.  Structured Group Psychotherapy for Bipolar Disorder. The Life Goals Program, 2nd Edition (New York, Springer, 2003).  In addition, the first edition has been published in French (Aubrey JM (trans).
Thérapie de Groupe pour le Trouble Bipolaire: Un Approche Structurée.  Geneva, Switzerland, Éditions Médecine et Hygiene, 2001.), and an unpublished Spanish version is also available from Dr. Bauer.
Use of the Life Goals Program in a Research Project based in a community setting:
From its inception, the Life Goals Program was developed to be ideally suited for implementation in community settings. The group format allows a number of individuals to interact with one group therapist, the instructions are simple, and reading and writing tasks needed are not prohibitively complex.  Dr. Martha Sajatovic MD, and Dr. Marilyn Davies PhD, both with the Department of Psychiatry at Case

Western Reserve University in Cleveland, Ohio, U.S.A. have recently begun a research study which tests the effects of the Life Goals Program on attitudes and behaviours in taking medication among patients with bipolar disorder. This project is supported by research grants from the National Institute of Mental Health (P20 MH066054-01A1 and K23 MH065599-01A2) and from the Woodruff Foundation.
The goal of this research study is to examine how a psychosocial intervention based upon a collaborative treatment model affects treatment adherence (how closely an individual sticks to his prescribed medication schedule). This is a prospective, randomized, controlled study of the effects on treatment adherence of adding a psychoeducational intervention (The Life Goals Program) to the medical management (Usual Care) of outpatients with bipolar disorder who attend a community mental health clinic. The community mental health clinic (NorthEast Ohio Health Services) is located in a suburban setting and provides a diverse array of specialized mental health services including counselling for individuals and families as well as medication management. 

As of December 2003 there have been 76 patients recruited. The randomisation ensures that half of the participants are recruited to the psychotherapeutic intervention and half of the participants are recruited to the “treatment as usual” control arm.  Preliminary data analysis finds that the average age of patients participating is 43.9 years, ethnic composition 34% African- American, 66% Caucasian.  Substance abuse is very common in the patients involved in the study, with 65% of individuals having either current substance abuse, or a past history of substance abuse. The study investigators have hypothesized that the Life Goals group will improve treatment adherence attitudes among individuals with bipolar disorder. Preliminary findings form the first group participants (see changes in treatment attitude

scores on Figure 1) support this hypothesis, as patients involved in the Life Goals intervention had significant improvement in attitudes towards medication after three months (p<. 05). Patients in usual care had no change in attitudes towards medication.  A larger sample of study patients followed over the anticipated 1- year study trajectory is needed to confirm these preliminary findings.  Currently the study continues to actively enroll participants.  More preliminary results on the primary outcome measures of adherence attitudes and adherence behaviours will be available and analyzed in 2004.

 Fig. 10 (Grafico, Didascalia: “Changes in treatment attitudes as a result of psychosocial intervention.  (Increase in attitude score indicates more positive attitudes towards treatment)”

Traduzione:“I cambiamenti dell’aderenza alla cura come risultato dell’intervento psicosociale (il maggiore punteggio attitudinale indica una migliore adesione alla cura) ”

Implementing a research project in a community setting poses challenges not generally found in academic settings.  These include large, often overwhelming caseloads of clinic staff, and patient populations that tend to be more severely ill, with more life/family instability, poverty and comorbid substance use than that typically seen in pure “academic” or university settings.  However, the data obtained from conducting research in community settings most closely represents the “real world”, and provides a practical base upon which to design and develop interventions that will benefit the greatest number of individuals. There has been a very positive response from Life Goals participants.
Verbatim comments from patients in the first group cohort include: “This is an exciting project.  It really has potential! ”, “ The education part really helps me…”.